Current Preprints (updated September 2024)

  1. Rena Emond, Jeffrey West, Vince Grolmusz, Patrick Cosgrove, Aritro Nath, Alexander R. A. Anderson, Andrea H. Bild. (2024) A novel combination therapy for ER+ breast cancer suppresses drug resistance via an evolutionary double-bind. Doi: 10.1101/2024.09.03.611032.
  2. Amy Milne, Philip K. Maini, Alexander R.A. Anderson, and Noemi Picco. (2024) The role of environmentally mediated drug resistance in facilitating the spatial distribution of residual disease. Doi: 10.21203/rs.3.rs-4526427/v1.
  3. Bina Desai, Tatiana Miti, Sandhya Prabhakaran, Daria Miroshnychenko, Menkara Henry, Viktoriya Marusyk, Chandler Gatenbee, Marilyn Bui, Jacob Scott, Philipp M Altrock, Eric Haura, Alexander R. A. Anderson, David Basanta, Andriy Marusyk. (2024) Peristromal niches protect lung cancers from targeted therapies through a combined effect of multiple molecular mediators. Doi: 10.1101/2024.04.24.590626.
  4. Kimberly A Luddy, Jeffrey West, Mark Robertson-Tessi, Bina Desai, Taylor M. Bursell, Sarah Barrett, Jacintha O’Sullivan, Laure Marignol, Robert A Gatenby,Joel S Brown, Alexander R. A. Anderson and Cliona O’Farrelly. (2024) Evolutionary double-bind treatment using radiotherapy and NK cell-based immunotherapy in prostate cancer. Doi: 10.1101/2024.03.11.584452.
  5. Daniel S. Thomas, Alexander R. A. Anderson, Luis H. Cisneros and Carlo C. Maley. (2023) In Silico Investigations of Adaptive Therapy Using Two Cytotoxic or Two Cytostatic Drugs. Doi: 10.1101/2023.05.12.540626.
  6. Daniel S. Thomas, Alexander R. A. Anderson, Luis H. Cisneros and Carlo C. Maley. (2023) In Silico Investigations of Adaptive Therapy Using a Single Cytotoxic or a Single Cytostatic Drug. Doi: 10.1101/2023.05.14.540580.
  7. Mark Robertson-Tessi, Joel S. Brown, Maria I. Poole, Matthew Johnson, Andriy Marusyk, Jill A. Gallaher, Kimberly A. Luddy, Christopher J. Whelan, Jeffrey West, Maximillian Strobl, Virginia Turati, Heiko Enderling, Michael J. Schell, AikChoon Tan, Terry Boyle, Rikesh Makanji, Joaquim Farinhas, Hatem Soliman, Dawn Lemanne, Robert A. Gatenby, Damon R. Reed, Alexander R. A. Anderson, and Christine H. Chung. (2023) Feasibility of an Evolutionary Tumor Board for Generating Novel Personalized Therapeutic Strategies. Doi: 10.1101/2023.01.18.23284628.
  8. Sandhya Prabhakaran, Chandler Gatenbee, Mark Robertson-Tessi, Amer A. Beg, Jhanelle Gray, Scott Antonia, Robert A. Gatenby, Alexander R. A. Anderson. (2022) Distinct tumor-immune ecologies in NSCLC patients predict progression and define a clinical biomarker of therapy response. Doi: 10.1101/2022.10.22.513219.
  9. Gregory J. Kimmel, Jeffrey West, Mehdi Damaghi, Alexander R. A. Anderson, Philipp M. Altrock. (2021) Local contact inhibition leads to universal principles of cell population growth. arXiv:2108.10000 [q-bio.PE].
  10. Jeffrey West, Maximilian Strobl, Cole Armagost, Richard Miles, Andriy Marusyk, Alexander R. A. Anderson. (2020) Antifragile therapy. https://doi.org/10.1101/2020.10.08.331678.
  11. Chandler Gatenbee, Jeffrey West, Annie M. Baker, Nafia Guljar, Louise Jones, Trevor A. Graham, Mark Robertson-Tessi, Alexander R. A. Anderson. (2019) Macrophage-mediated immunoediting drives ductal carcinoma evolution: Space is the game changer. https://doi.org/10.1101/594598.

Refereed Journal Publications (updated September 2024)

  1. Nancy Villa, Xiaoqing Yu, Joseph Johnson, Gustavo Borjas, Jasreman Dhillon, Carlos Moran, Youngchul Kim, Natasha Francis, Denise Dorman, John Powers, Wade Sexton, Philippe Spiess, Michael Poch, Logan Zemp, Scott Gilbert, Jingsong Zhang, Julio Pow-Sang, Alexander R.A. Anderson, Tingyi Li, Xuefeng Wang, Daniel Grass, James Burke, Colin Dinney, Paulo Rodriguez, Rohit Jain, James Mulé, Jose Conejo-Garcia, Roger Li. (2024) Oncolytic Immunotherapy with Nivolumab in Muscle-Invasive Bladder Cancer: A Phase 1b Trial. Nature Medicine, Accepted.
  2. Sadegh Marzban, Sonal Srivastava, Sharon Kartika, Rafael Bravo, Rachel Safriel, Aidan Zarski, Alexander R. A. Anderson, Christine H. Chung, Antonio L. Amelio, Jeffrey West. (2024) Spatial interactions modulate tumor growth and immune infiltration. NPJ Systems Biology and Applications, 10: 106. Doi: 10.1038/s41540-024-00438-1.
  3. Aguadé-Gorgorió, Alexander R.A. Anderson and Ricard Solé. (2024) Modeling tumors as complex ecosystems. iScience, 27(9): 110699. Doi: 10.1016/j.isci.2024.110699.
  4. Philippe Weitz, Masi Valkonen, Leslie Solorzano, Circe Carr, Kimmo Kartasalo, Constance Boissin, Sonja Koivukoski, Aino Kuusela, Dusan Rasic, Yanbo Fenga, Sandra Sinius Pouplier, Abhinav Sharma, Kajsa Ledesma Eriksson, Stephanie Robertson, Christian Marzahl, Chandler D. Gatenbee, Alexander R.A. Anderson, Marek Wodzinski, Artur Jurgas, Niccol`o Marini, Manfredo Atzori, Henning Müller, Daniel Budelmann, Nick Weiss, Stefan Heldmann, Johannes Lotz, Jelmer M. Wolterink, Bruno De Santi, Abhijeet Patil, Amit Sethi, Satoshi Kondo, Satoshi Kasai, Kousuke Hirasawa, Mahtab Farrokh, Neeraj Kumar, Russell Greiner, Leena Latonen, Anne-Vibeke Laenkholm, Johan Hartman, Pekka Ruusuvuori, Mattias Rantalaine. (2024) The ACROBAT 2022 challenge: Automatic registration of breast cancer tissue. Medical Image Analysis, 97: 103257. Doi: 10.1016/j.media.2024.103257.
  5. Ugoma Onubogu, Chandler D. Gatenbee, Sandhya Prabhakaran, Kelsey Wolfe. Benjamin Oakes, Roberto Salatino, Rachael Vaubel, Oszkar Szentirmai, Alexander R. A. Anderson, Michalina Janiszewska. (2024) Spatial analysis of recurrent glioblastoma reveals perivascular niche organization. JCI Insight, 9(12):e179853. Doi: 10.1172/jci.insight.179853.
  6. Maximilian Strobl, Alexandra Martin, Jeffrey West, Jill Gallaher, Mark Robertson-Tessi, Robert Gatenby, Robert Wenham, Philip Maini, Mehdi Damaghi, Alexander R. A. Anderson. (2024) To modulate or to skip: De-escalating PARP inhibitor maintenance therapy in ovarian cancer using adaptive therapy. Cell Systems, 15(6): 510–525. Doi: 10.1016/j.cels.2024.04.003.
  7. Kit Gallagher, Maximilian Strobl, Robert Gatenby, Philip Maini, Alexander R. A. Anderson. (2024) Mathematical Model-Driven Deep Learning Enables Personalized Adaptive Therapy. Cancer Research, Accpepted. Doi: 10.1158/0008-5472.CAN-23-2040.
  8. Luke Pierik, Patricia McDonald, Alexander R. A. Anderson and Jeffrey West. (2024) Second-Order Effects of Chemotherapy Pharmacodynamics and Pharmacokinetics on Tumor Regression and Cachexia. Bulletin of Mathematical Biology, 86:47. Doi: 10.1007/s11538-024-01278-0.
  9. Jeffrey West, Frederika Rentzeperis, Casey Adam, Rafael Bravo, Kimberly A. Luddy, Mark Robertson-Tessi, Alexander R. A. Anderson. (2024) Tumor-immune metaphenotypes orchestrate an evolutionary bottleneck that promotes metabolic transformation. Frontiers in Immunology, 15:1323319. Doi: 10.3389/fimmu.2024.1323319.
  10. Sareh Seyedi, Ruthanne Teo, Luke Foster, Daniel Saha, Lida Mina, Donald Northfelt, Karen S. Anderson, Darryl Shibata, Robert Gatenby, Luis Cisneros, Brigid Troan, Alexander R. A. Anderson, Carlo C. Maley. (2024) Testing Adaptive Therapy Protocols Using Gemcitabine and Capecitabine in a Preclinical Model of Endocrine-Resistant Breast Cancer. Cancers 16(2), 257. Doi: 10.3390/cancers16020257.
  11. Maximilian Strobl, Jill Gallaher, Mark Robertson-Tessi, Jeffrey West, Alexander R. A. Anderson. (2023) Treatment of evolving cancers will require dynamic decision support. Annals of Oncology, 34(10): 867-884. Doi: 10.1016/j.annonc.2023.08.008. This was the October Cover article!
  12. Chandler D. Gatenbee, Ann-Marie Baker, Ottilie Swinyard, Sandhya Prabhakaran, Robbert J. C. Slebos, Gunjan Mandal, Eoghan Mulholland, Noemi Andor, Andriy Marusyk, Simon Leedham, Jose R. Conejo-Garcia, Christine H. Chung, Mark Robertson-Tessi, Trevor A. Graham, Alexander R. A. Anderson. (2023) VALIS: Virtual Alignment of pathoLogy Image Series for multi-gigapixel whole slide images. Nature Communications, 14, 4502. Doi: 10.1038/s41467-023-40218-9.
  13. Jad Chahoud, Alexander R.A. Anderson, Jingsong Zhang, Joel Brown and Robert A. Gatenby. (2023) Evolutionary Dynamics and Intermittent Therapy for Metastatic Cancers. Journal of Clinical Oncology. Doi: 10.1200/JCO.23.00647.
  14. Jill Gallaher, Maximilian Strobl, Jeffrey West, Jingsong Zhang, Robert Gatenby, Mark Robertson-Tessi, Alexander R. A. Anderson. (2023) Intermetastatic and Intrametastatic Heterogeneity Shapes Adaptive Therapy Cycling Dynamics. Cancer Research, 83 (16): 2775–2789. Doi: 10.1158/0008-5472.CAN-22-2558. This was the August 15th Cover article!
  15. Frederick R. Adler, Alexander R. A. Anderson, Abhinav Bhushan, Paul Bogdan, Jose Javier Bravo-Cordero, Amy Brock, Yun Chen, Edna Cukierman, Kathleen E. DelGiorno, Gerald V. Denis, Meghan C. Ferrall-Fairbanks, Zev J. Gartner, Ronald N. Germain, Deborah M. Gordon, Ginger Hunter, Mohit Kumar Jolly, Loukia Georgiou Karacosta, Karthikeyan Mythreye, Parag Katira, Rajan P. Kulkarni, Matthew L. Kutys, Arthur D. Lander, Ashley M. Laughney, Herbert Levine, Emil Lou, Pedro R. Lowenstein, Kristyn S. Masters, Dana Pe'er, Shelly R. Peyton, Manu O. Platt, Jeremy E. Purvis, Gerald Quon, Jennifer K. Richer, Nicole C. Riddle, Analiz Rodriguez, Joshua C. Snyder, Gregory L. Szeto, Claire J. Tomlin, Itai Yanai, Ioannis K. Zervantonakis, Hannah Dueck. (2023) Modeling collective cell behavior in cancer: perspectives from an interdisciplinary conversation. Cell Systems, 14(4): 252-257, Doi: 10.1016/j.cels.2023.03.002.
  16. Jeffrey West, Fred Adler, Jill Gallaher, Maximilian Strobl, Renee Brady-Nicholls, Joel S. Brown, Mark Robertson-Tessi, Eunjung Kim, Robert Noble, Yannick Viossat, David Basanta, Alexander R. A. Anderson. (2023) A survey of open questions in adaptive therapy: bridging mathematics and clinical translation. eLife 12:e84263, Doi: 10.7554/eLife.84263.
  17. Prakash Kulkarni, H. Steven Wiley, Herbert Levine, Herbert Sauro, Alexander R. A. Anderson, Stephen T.C. Wong, Aaron S. Meyer, Puneeth Iyengar, Kevin Corlette, Kristin Swanson, Atish Mohanty, Supriyo Bhattacharya, Amit Patel, Vinay Jain, Ravi Salgia. (2023) Addressing the genetic/nongenetic duality in cancer with systems biology. Trends in Cancer, 9(3): 185-187, Doi: 10.1016/j.trecan.2022.12.004.
  18. Jeffrey West, Mark Robertson-Tessi, Alexander R. A. Anderson. (2022) Agent-based methods facilitate integrative science in cancer. Trends in Cell Biology, 33 (4):300-311, Doi: 10.1016/j.tcb.2022.10.006. This was the April issue cover article!
  19. Zhang, J., Gallaher, J., Cunningham, J.J., Choi, J.W., Ionescu, F., Chatwal, M.S., Jain, R., Kim, Y., Wang, L., Brown, J.S., Anderson, A.R., Gatenby, R.A. (2022) A Phase 1b Adaptive Androgen Deprivation Therapy Trial in Metastatic Castration Sensitive Prostate Cancer. Cancers, 14, 5225, Doi: 10.3390/cancers14215225.
  20. Ryan O. Schenck, Eunjung Kim, Rafael R. Bravo, Jeffrey West, Simon Leedham, Darryl Shibata, Alexander R. A. Anderson. (2022) Homeostasis Limits Keratinocyte Evolution. PNAS, 119 (35) e2006487119, https://www.pnas.org/doi/10.1073/pnas.2006487119.
  21. Sandhya Prabhakaran, Chandler Gatenbee, Alexander R. A. Anderson. (2022) Developing tools for analyzing and viewing multiplexed images, Patterns, 3, 100549, Doi: 10.1016/j.patter.2022.100549.
  22. Sandhya Prabhakaran, Chandler Gatenbee, Mark Robertson-Tessi, Jeffrey West, Amer A. Beg, Jhanelle Gray, Scott Antonia, Robert A. Gatenby, Alexander R. A. Anderson. (2022) Mistic: an open-source multiplexed image t-SNE viewer. Patterns, 3, 100523, Doi: 10.1016/j.patter.2022.100523.
  23. Daniel S. Thomas, Luis H. Cisneros, Alexander R. A. Anderson and Carlo C. Maley. (2022) In Silico Investigations of Multi-Drug Adaptive Therapy Protocols. Cancers, 14(11):2699, Doi.org/10.3390/cancers14112699.
  24. Carmen M. Anadon, Xiaoqing Yu, Kay Hänggi, Subir Biswas, Ricardo A. Chaurio, Alexandra Martin, Kyle K. Payne, Gunjan Mandal, Patrick Innamarato, Carly M. Harro, Jessica A. Mine, Kimberly B. Sprenger, Carla Cortina, John J. Powers, Tara Lee Costich, Bradford A. Perez, Chandler D. Gatenbee, Sandhya Prabhakaran, Douglas Marchion, Mirjam H.M. Heemskerk, Tyler J. Curiel, Alexander R. Anderson, Robert M. Wenham, Paulo C.Rodriguez, Jose R. Conejo-Garcia. (2022) Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells. Cancer Cell, 40(5): 545-557.e13. DOI: 10.1016/j.ccell.2022.03.008.
  25. Maximilian Strobl, Jill Gallaher, Jeffrey West, Mark Robertson-Tessi, Philip Maini, Alexander R. A. Anderson. (2022) Spatial structure impacts adaptive therapy by shaping intra-tumoral competition. Communications Medicine, 2, 46. DOI: 10.1038/s43856-022-00110-x.
  26. Ryan O Schenck, Gabriel Brosula, Jeffrey West, Simon Leedham, Darryl Shibata, Alexander R. A. Anderson. (2022) Gattaca: Base pair resolution mutation tracking for somatic evolution studies using agent-based models. Molecular Biology and Evolution, Accepted, https://doi.org/10.1093/molbev/msac058.
  27. Chandler D. Gatenbee, Ann-Marie Baker, Ryan O. Schenck, Maximilian Strobl, Jeffrey West, Margarida P. Neves, Sara Yakub Hasan, Eszter Lakatos, Pierre Martinez, William CH Cross, Marnix Jansen, Manuel Rodriguez-Justo, Christopher J. Whelan, Andrea Sottoriva, Simon Leedham, Mark Robertson-Tessi, Trevor A. Graham, Alexander R.A. Anderson. (2022) Immunosuppressive niche engineering at the onset of human colorectal cancer. Nature Communications, 13, 1798. https://doi.org/10.1038/s41467-022-29027-8.
  28. Jasmine Foo, David Basanta, Russell C Rockne, Carly Strelez, Curran Shah, Kimya Ghaffarian, Shannon M. Mumenthaler, Kelly Mitchell, Justin D. Lathia, David Frankhouser, Sergio Branciamore, Ya-Huei Kuo, Guido Marcucci, Robert Vander Velde, Andriy Marusyk, Sui Huang, Kishore Hari, Mohit Kumar Jolly, Haralampos Hatzikirou, Kamrine E. Poels, Mary E. Spilker, Blerta Shtylla, Mark Robertson-Tessi, Alexander R.A Anderson. (2022) Roadmap on Plasticity and Epigenetics in Cancer. Physical Biology, 19, 031501. DOI 10.1088/1478-3975/ac4ee2.
  29. Calum Gabbutt, Ryan O Schenck, Dan Weisenberger, Christopher Kimberley, Alison Berner, Jacob Househam, Eszter Lakatos, Mark Robertson-Tessi, Isabel Martin, Roshani Patel, Sue Clark, Andrew Latchford, Christopher Barnes, Simon J Leedham, Alexander R. A. Anderson, Trevor A. Graham, Darryl Shibata. (2022) Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues. Nature Biotechnology, DOI:10.1038/s41587-021-01109-w.
  30. Mandal G, Biswas S, Anadon CM, Yu X, Gatenbee CD, Prabhakaran S, Payne KK, Chaurio RA, Martin A, Innamarato PP, Moran C, Powers JJ, Harro CM, Mine JA, Sprenger KB, Rigolizzo KE, Wang X, Curiel TJ, Rodriguez PC, Anderson AR, Saglam O, Conejo-Garcia JR. (2021). IgA-dominated humoral immune responses govern patients’ outcome in endometrial cancer. Cancer Research, doi: 10.1158/0008-5472.CAN-21-2376.
  31. Tyler Cassidy, Daniel Nichol, Mark Robertson-Tessi, Morgan Craig, Alexander R. A. Anderson. (2021) The role of memory in non-genetic inheritance and its impact on cancer treatment resistance. Plos Comp. Biology, 17(8): e1009348. Doi.org/10.1371/journal.pcbi.1009348.
  32. Jeffrey West, Ryan Schenck, Chandler Gatenbee, Mark Robertson-Tessi, Alexander R. A. Anderson. (2021) Normal tissue architecture determines the evolutionary course of cancer. Nature Communications, 12, 2060. https://doi.org/10.1038/s41467-021-22123-1.
  33. Eunjung Kim, Joel S. Brown, Zeynep Eroglu, Alexander R.A. Anderson. (2021) Adaptive Therapy for Metastatic Melanoma: Predictions from Patient Calibrated Mathematical Models. Cancers, 13(4), 823. https://doi.org/10.3390/cancers13040823.
  34. Maximilian Strobl, Jeffrey West, Joel Brown, Robert Gatenby, Philip Maini, Alexander R. A. Anderson. (2021) Turnover modulates the need for a cost of resistance in adaptive therapy. Cancer Research, 81(4), 1135–47. Doi: 10.1158/0008-5472.CAN-20-0806. This was the February 15th Cover article!
  35. Subir Biswas, Gunjan Mandal, Kyle K. Payne, Carmen M. Anadon, Chandler D. Gatenbee, Ricardo A. Chaurio, Tara Lee Costich, Carlos Moran, Carly M. Harro, Kristen E. Rigolizzo, Jessica A. Mine, Jimena Trillo-Tinoco, Naoko Sasamoto, Kathryn L. Terry, Douglas Marchion, Andrea Buras, Robert M. Wenham, Xiaoqing Yu, Mary K. Townsend, Shelley S. Tworoger, Paulo C. Rodriguez, Alexander R. A. Anderson and Jose R. Conejo-Garcia. (2021) IgA transcytosis and antigen recognition govern ovarian cancer immunity. Nature, https://doi.org/10.1038/s41586-020-03144-0.
  36. Mehdi Damaghi, Jeffrey West, Mark Robertson-Tessi, Liping Xu, Meghan C. Ferrall-Fairbanks, Paul A. Stewart, Erez Persi, Brooke L. Fridley, Philipp M. Altrock, Robert A. Gatenby, Peter A. Sims, Alexander R. A. Anderson, Robert J. Gillies. (2021) The Harsh Microenvironment in Early Breast Cancer Selects for a Warburg Phenotype. PNAS, 118 (3) e2011342118, https://doi.org/10.1073/pnas.2011342118.
  37. Jeffrey West, Yongqian Ma, Artem Kaznatcheev, Alexander R. A. Anderson. (2020) IsoMaTrix: a framework to visualize the isoclines of matrix games and quantify uncertainty in structured populations. Bioinformatics, btaa1025, https://doi.org/10.1093/bioinformatics/btaa1025.
  38. Sierra A. Walker, Anthony Pham, Sara Nizzero, Mingee Kim, Bob Riter, Julie Bletz, Sheila Judge, Benette Phillips, Dorottya Noble, Diana Murray, Erin Wetzel, Susan Samson, Mariah McMahon, Carl Flink, Jennifer Couch, Claire Tomlin, Kristin Swanson, Alexander R.A. Anderson, David Odde, Haifa Shen, Shannon Hughes, Nastaran Zahir, Heiko Enderling, Joy Wolfram. (2020) Education and Outreach in Physical Sciences in Oncology. Trends in Cancer. https://doi.org/10.1016/j.trecan.2020.10.007.
  39. Susan C. Massey, Paula Whitmire, Tatum E.Doyle, Joseph E. Ippolito, Maciej M. Mrugala, Leland S. Hue, Peter Canoll, Alexander R.A. Anderson, Melissa A. Wilson, Susan M. Fitzpatrick, Margaret M. McCarthy, Joshua B. Rubin, Kristin R.Swanson. (2020) Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma. Cancer Letters, https://doi.org/10.1016/j.canlet.2020.07.030.
  40. Derek S Park, Kimberly A Luddy, Mark Robertson-Tessi, Cliona O'Farrelly, Robert A Gatenby and Alexander R. A. Anderson. (2020) Searching for Goldilocks: How evolution and ecology can help uncover more effective patient-specific chemotherapies. Cancer Research, 80(23): 5147-5154. DOI: 10.1158/0008-5472.CAN-19-3981.
  41. Eszter Lakatos, Marc J. Williams, Ryan O. Schenck, William C. H. Cross, Jacob Househam, Benjamin Werner, Chandler Gatenbee, Mark Robertson-Tessi, Chris P. Barnes, Alexander R. A. Anderson, Andrea Sottoriva, Trevor A. Graham. (2020) Evolutionary dynamics of neoantigens in growing tumours. Nature Genetics, https://doi.org/10.1038/s41588-020-0687-1.
  42. Aleksandra Ardaševa, Alexander R. A. Anderson, Robert A. Gatenby, Helen M. Byrne, Philip K. Maini, Tommaso Lorenzi. (2020) A comparative study between discrete and continuum models for the evolution of competing phenotype-structured cell populations in dynamical environments. Physical Review E, 102: 042404; https://doi.org/10.1103/PhysRevE.102.042404.
  43. Chandler D. Gatenbee, Emily S. Minor, Robbert J. C. Slebos, Christine H. Chung, Alexander R. A. Anderson. (2020) Histoecology: Applying Ecological Principles and Approaches to Describe and Predict Tumor Ecosystem Dynamics Across Space and Time. Cancer Control 27:1-7. DOI: 10.1177/1073274820946804.
  44. Heiko Enderling, Philipp M. Altrock, Noemi Andor, David Basanta, Joel S. Brown, Robert A. Gatenby, Andriy Marusyk, Katarzyna A. Rejniak, Ariosto Silva & Alexander R. A. Anderson. (2020) High School Internship Program in Integrated Mathematical Oncology (HIP IMO): Five-Year Experience at Moffitt Cancer Center. Bulletin of Mathematical Biology 82:91. https://doi.org/10.1007/s11538-020-00768-1.
  45. J. Hernandez-Prera, P. Valderrabano, C. Ramón, J. Creed, J. de la Iglesia, R. Slebos, B. Centeno, V. Tarasova, J. Hallanger-Johnson, C. Veloski, K. Otto, B. Wenig, S. Yoder, C. Lam, D. Park, A. R. A. Anderson, N. Raghunand, A. Berglund, J. Caudell, T. Gerke, C. Chung. (2020) Molecular determinants of Thyroid nodules with indeterminate cytology and RAS mutations. Thyroid, https://doi.org/10.1089/thy.2019.0650.
  46. Aleksandra Ardaševa, Robert A. Gatenby, Alexander R. A. Anderson, Helen M. Byrne, Philip K. Maini, Tommaso Lorenzi. (2020) A mathematical dissection of the adaptation of cell populations to fluctuating oxygen levels. Bulletin of Mathematical Biology, 82: 81; https://doi.org/10.1007/s11538-020-00754-7.
  47. Ziv Frankenstein, David Basanta, Omar E. Franco, Yan Gao, Rodrigo A. Javier, Douglas W. Strand, MinJae Lee, Simon W. Hayward, Gustavo Ayala, Alexander R. A. Anderson. (2020) Stromal Reactivity Differentially Drives Tumor Cell Evolution and Prostate Cancer Progression. Nature Ecology and Evolution. https://doi.org/10.1038/s41559-020-1157-y.
  48. Jeffrey West, Li You, Jingsong Zhang, Robert A. Gatenby, Joel Brown, Paul K Newton, Alexander R. A. Anderson. (2020) Towards multi-drug adaptive therapy. Cancer Research 80(7): 1578-1589; DOI: 10.1158/0008-5472.CAN-19-2669. This was the April 1st Cover article!
  49. Rafael Bravo, Etienne Baratchart, Jeffrey West, Ryan O. Schenck, Anna Miller, Jill Gallaher, Chandler Gatenbee, David Basanta, Mark Robertson-Tessi, Alexander R. A. Anderson. (2020) Hybrid Automata Library: A flexible platform for hybrid modeling with real-time visualization. Plos Computational Biology 16(3): e1007635. https://doi.org/10.1371/journal.pcbi.1007635. Check our dedicated website HAL!
  50. Jill A. Gallaher, Susan C. Massey, Andrea Hawkins-Daarud, Sonal S. Noticewala, Russell C. Rockne, Sandra K. Johnston, Luis Gonzalez-Cuyar, Joseph Juliano, Orlando Gil, Kristin R. Swanson, Peter Canoll and Alexander R.A. Anderson. (2020) From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response. PloS Computational Biology 16(2): e1007672. https://doi.org/10.1371/journal.pcbi.1007672.
  51. Maximilian A. R. Strobl, Andrew L. Krause, Mehdi Damaghi, Robert Gillies, Alexander R. A. Anderson, Philip K. Maini. (2019) Mix & Match: Phenotypic coexistence as a key facilitator of solid tumour invasion. Bulletin of Mathematical Biology, 82: 15. https://doi.org/10.1007/s11538-019-00675-0.
  52. Chandler D. Gatenbee, Ryan O. Schenck, Rafael Bravo, Alexander R. A. Anderson. (2019) EvoFreq: Visualization of the Evolutionary Frequencies of Sequence and Model Data. Accepted, BMC Bioinformatics, 20(710), https://doi.org/10.1186/s12859-019-3173-y.
  53. Daniel Nichol, Mark Robertson-Tessi, Alexander R. A. Anderson, Peter Jeavons. (2019) Model Genotype-Phenotype Mappings and the Algorithmic Structure of Evolution. Royal Society Interface. 10.1098/rsif.2019.0332.
  54. Aleksandra Ardaševa, Robert A. Gatenby, Alexander R. A. Anderson, Helen M. Byrne, Philip K. Maini, Tommaso Lorenzi. (2019) Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments. Accepted, Journal of Mathematical Biology. 10.1007/s00285-019-01441-5.
  55. Inna Smalley, Eunjung Kim, Jiannong Li, Paige Spence, Clayton J. Wyatt, Zeynep Eroglu, Vernon K. Sondak, Jane L. Messina, Nalan Akgul Babacan, Silvya Stuchi Maria-Engler, Lesley De Armas, Sion L. Williams, Robert A. Gatenby, Y. Ann Chen, Alexander R.A. Anderson, Keiran S.M. Smalley. (2019) Leveraging transcriptional dynamics to improve BRAF inhibitor responses in melanoma. EBioMedicine 48:178-190. https://doi.org/10.1016/j.ebiom.2019.09.023.
  56. Jacob G Scott, Philip K Maini, Alexander RA Anderson, Alexander G Fletcher. (2019) Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model. Accepted, Systematic Biology. https://doi.org/10.1101/334946.
  57. Derek S. Park, Mark Robertson-Tessi, Philip Maini, Michael B Bonsall, Robert A Gatenby, Alexander R. A. Anderson. (2019) The Goldilocks Window of Personalized Chemotherapy: Getting the Immune Response Just Right. Cancer Research, 79 (20): 5302-5315. Doi: 10.1158/0008-5472.CAN-18-3712. This was the October 15th Cover article!
  58. Asmaa El-Kenawi, Chandler Gatenbee, Mark Robertson-Tessi, Rafael Bravo, Jasreman Dhillon, Yoganand Balagurunathan, Anders Berglund, Naveen Visvakarma, Arig Ibrahim-Hashim, Jung Choi, Kimberly Luddy, Robert Gatenby, Shari-Pilon Thomas, Alexander R. A. Anderson, Brian Ruffell, Robert Gillies. (2019) Acidity promotes tumor progression by altering macrophage phenotype in prostate cancer. British Journal of Cancer, https://doi.org/10.1038/s41416-019-0542-2.
  59. Russell C. Rockne, Andrea Hawkins-Daarud, Kristin R. Swanson, James P Sluka, James A. Glazier, Paul Macklin, David Hormuth, Angela M Jarrett, Ernesto Augutso Bueno da Fonseca Lima, J Oden, George Biros, Thomas E Yankeelov, Kit Curtius, Ibrahim Al Bakir, Dominik Wodarz, Natalia Komarova, Luis Aparicio, Mykola Bordyuh, Raul Rabadan, Stacey Finley, Heiko Enderling, Jimmy J. Caudell, Eduardo G Moros, Alexander R A Anderson, Robert Gatenby, Artem Kaznatcheev, Peter Jeavons, Nikhil Krishnan, Julia Pelesko, Raoul R. Wadhwa, Nara Yoon, Daniel Nichol, Andriy Marusyk, Michael Hinczewski and Jacob G. Scott. (2019) The 2019 Mathematical Oncology Roadmap. Physical Biology, https://iopscience.iop.org/article/10.1088/1478-3975/ab1a09/.
  60. Ryan O. Schenck, Eszter Lakatos, Chandler Gatenbee, Trevor A. Graham, Alexander R. A. Anderson. (2019) NeoPredPipe: High-Throughput Neoantigen Prediction and Recognition Potential Pipeline. BMC Bioinformatics, 20:264, https://doi.org/10.1186/s12859-019-2876-4.
  61. Jeffrey B West, Mina N Dinh, Joel S Brown, Jingsong Zhang, Alexander R. A. Anderson and Robert A Gatenby. (2019) Multidrug cancer therapy in metastatic castrate-resistant prostate cancer: An evolution-based strategy. Clinical Cancer Research, DOI: 10.1158/1078-0432.CCR-19-0006.
  62. Derek S. Park, Afua A. Akuffo, David E. Muench, H. Leighton Grimes, Pearlie K. Epling-Burnette, Philip K. Maini, Alexander R. A. Anderson, Michael B. Bonsall. (2019) Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation. PloS Comp. Biol, 15(4): e1006913, https://doi.org/10.1371/journal.pcbi.1006913.
  63. Susan Christine Massey, Andrea Hawkins-Daarud, Jill Gallaher, Alexander R. A. Anderson, Peter Canoll, Kristin R. Swanson. (2019) Lesion Dynamics Under Varying Paracrine PDGF Signaling in Brain Tissue. Bulletin of Mathematical Biology, doi.org/10.1007/s11538-019-00587-z.
  64. Jill A. Gallaher, Joel Brown, and Alexander R. A. Anderson. (2019) The dynamic tumor ecosystem: how cell turnover and trade-offs affect cancer evolution. Scientific Reports, 9: 2425, s41598-019-39636-x. Also click here for interactive supplamental movies and code.
  65. Jeffrey West, Mark Robertson-Tessi, Kimberly Luddy, Derek S. Park, Drew F.K. Williamson, Cathal Harmon, Hung T. Khong, Joel Brown, Alexander R.A. Anderson. (2019) The immune checkpoint kick start: Optimization of neoadjuvant combination therapy using game theory. JCO Clinical Cancer Informatics, doi/10.1200/CCI.18.00078.
  66. Jacob G. Scott, Andrew Dhawan, Anita Hjelmeland, Justin Lathia, Masahiro Hitomi, Alexander G. Fletcher, Philip K. Maini, Alexander R. A. Anderson. (2019) Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces. Current Stem Cell Reports, DOI 10.1007/s40778-019-0153-0.
  67. Daniel Nichol, Joseph Rutter, Christopher Bryant, Andrea M. Hujer, Sai Lek, Mark D. Adams, Peter Jeavons, Alexander Anderson, Robert Bonomo, Jacob Scott. (2019) Antibiotic collateral sensitivity is contingent on the repeatability of evolution. Nature Communications 10: 334 https://doi.org/10.1038/s41467-018-08098-6.
  68. William Cross, Michal Kovac, Ville Mustonen, Daniel Temko, Hayley Davis, Ann-Marie Baker, Sujata Biswas, Roland Arnold, Laura Chegwidden, Chandler Gatenbee, Alexander Anderson, Viktor Koelzer, Pierre Martinez, Xiaowei Jiang, Enric Domingo, Dan Woodcock, Yun Feng, Monika Kovacova, Tim Maughan, S:CORT consortium, Marnix Jansen, Manuel Rodriguez-Justo, Shazad Ashraf, Richard Guy, Chris Cunningham, James East, David Wedge, Lai Mun Wang, Claire Palles, Karl Heinimann, Andrea Sottoriva, Simon Leedham, Trevor Graham, and Ian Tomlinson. (2018) The evolutionary landscape of colorectal tumorigenesis, Nature Ecology & Evolution 2:1661–1672.DOI: 10.1038/s41559-018-0642-z.
  69. Walker R, Poleszczuk J, Pilon-Thomas S, Kim S, Anderson ARA, Czerniecki BJ, Harrison LB, Moros EG, Enderling H. Immune interconnectivity of anatomically distant tumors as a potential mediator of systemic responses to local therapy. Sci Rep 2018 Jun; 8: (1) https://doi.org/10.1038/s41598-018-27718-1.
  70. Robert J. Gillies, Joel S. Brown, Alexander R. A. Anderson and Robert A. Gatenby. (2018) Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow. Nature Reviews Cancer, Accepted. https://doi.org/10.1038/s41568-018-0030-7.
  71. Alexander R. A. Anderson and Philip K. Maini. (2018) Mathematical Oncology. Bull Math Biol 80: 945. https://doi.org/10.1007/s11538-018-0423-5.
  72. Jill A. Gallaher, Pedro M. Enriquez-Navas, Kimberly A. Luddy, Robert A. Gatenby, Alexander R. A. Anderson. (2018) Spatial heterogeneity and evolutionary dynamics modulate time to recurrence in continuous and adaptive cancer therapies. Cancer Research, 78(8); 2127–39. https://doi.org/10.1101/128959.
  73. Eunjung Kim, Jae-Young Kim, Matthew A. Smith, Eric B. Haura, and Alexander R. A. Anderson. (2018) Cell signaling heterogeneity is modulated by both cell intrinsic and extrinsic mechanisms: An integrated approach to understanding targeted therapy, PLoS Biol 16(3): e2002930. https://doi.org/10.1371/journal. pbio.2002930.
  74. Joseph Juliano, Orlando Gil, Andrea Hawkins-Daarud, Sonal Noticewala, Russell C. Rockne, Jill Gallaher, Susan Christine Massey, Peter A. Sims, Alexander R. A. Anderson, Kristin R. Swanson, Peter Canoll. (2018) Comparative dynamics of microglial and glioma cell motility at the infiltrative margin of brain tumors. Roy. Soc. Interface, 15: 20170582, https://doi.org/10.1098/rsif.2017.0582.
  75. Yohsuke Yagawa, Mark Robertson-Tessi, Susan Zhou, Alexander R. A. Anderson, James Mule and Adam Mailloux. (2017) Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Scientific Reports, 7:15996, doi:10.1038/s41598-017-15924-2.
  76. Massey, S.C., Rockne, R.C., Hawkins-Daarud, A. Gallaher J., Anderson A.R.A., Canoll P., Swanson K.R. (2017) Simulating PDGF-Driven Glioma Growth and Invasion in an Anatomically Accurate Brain Domain. Bull Math Biol, doi.org/10.1007/s11538-017-0312-3.
  77. Carlo C. Maley, Athena Aktipis, Trevor A. Graham, Andrea Sottoriva, Amy M. Boddy, Michalina Janiszewska, Ariosto S. Silva, Marco Gerlinger, Yinyin Yuan, Kenneth J. Pienta, Karen S. Anderson, Robert Gatenby, Charles Swanton, David Posada, Chung-I Wu, Joshua D. Schiffman, E. Shelley Hwang, Kornelia Polyak, Alexander R. A. Anderson, Joel S. Brown, Mel Greaves, Darryl Shibata. (2017) Classifying the Evolutionary and Ecological Features of Neoplasms. Nature Reviews Cancer, doi:10.1038/nrc.2017.69.
  78. Philip Gerlee, David Basanta, Alexander R.A. Anderson. (2017) The Influence of Cellular Characteristics on the Evolution of Shape Homeostasis. Artificial Life 23(3): 424-448. doi: 10.1162/ARTL_a_00240, arXiv:1512.02474 [q-bio.TO].
  79. Noemi Picco, Erik Sahai, Philip K. Maini and Alexander R. A. Anderson. (2017) Integrating models to quantify environment mediated drug resistance. Cancer Research, Oct 1; 77(19):5409-5418. DOI: 10.1158/0008-5472.CAN-17-0835.
  80. Arig Ibrahim-Hashim, Mark Robertson-Tessi, Pedro M. Enriquez-Navas, Mehdi Damaghi,Yoganand Balagurunathan, Jonathan W. Wojtkowiak,Shonagh Russell, Yoonseok Kam, Mark C. Lloyd, Marilyn Bui, Joel Brown, Alexander R. A. Anderson, Robert J Gillies and Robert A. Gatenby. (2017) Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution. Cancer Research, 77(9): 2242-2254. doi:10.1158/0008-5472.CAN-16-2844. This was the May 1st Cover article!
  81. David Basanta, Alexander Anderson. (2017) Homeostasis Back and Forth: An Eco-Evolutionary Perspective of Cancer. CSH Perspectives in Medicine, Published in Advance March 13, 2017, doi: 10.1101/cshperspect.a028332.
  82. Daniel Nichol, Mark Robertson-Tessi, Peter Jeavons, Alexander RA Anderson. (2016) Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging. Genetics, Dec 1, 204(4):1523-1539. DOI: 10.1534/genetics.116.193474.
  83. Noemi Picco, Robert Gatenby, Alexander Anderson. (2016) Niche-Driven Stem Cell Plasticity and its Role in Cancer Progression. IEEE Trans. Biomed. Eng., March 2017; 64 (3): 528–537. DOI:10.1109/TBME.2016.2607183. 
  84. Eunjung Kim, Vito W. Rebecca, Keiran S.M. Smalley, Alexander R.A. Anderson. (2016) Phase i trials in melanoma: A framework to translate preclinical findings to the clinic. http://dx.doi.org/10.1016/j.ejca.2016.07.024. Eur. J. Cancer, Nov 2016; 67:213–222.
  85. Werner B, Scott JG, Sottoriva A, Anderson AR, Traulsen A, Altrock PM. (2016) The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories. Cancer Res., OnlineFirst February 1, 2016; doi:10.1158/0008-5472.CAN-15-2069.
  86. Scott JG, Fletcher AG, Anderson AR, Maini PK. (2015) Spatial metrics of tumour vascular organisation predict radiation efficacy in a computational model. PLoS Comput Biol, Jan 22; 12(1): e1004712. doi:10.1371/journal.pcbi.1004712.
  87. Nichol D, Jeavons P, Fletcher AG, Bonomo RA, Maini PK, Paul JL, Gatenby RA, Anderson AR, Scott JG. (2015) Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance. PLoS Comput Biol, Sep 11;11(9):e1004493, doi: 10.1371/journal.pcbi.1004493.
  88. Gerlee P. and Anderson AR. (2015) The evolution of carrying capacity in constrained and expanding tumour cell populations. Phys. Biol. 12 056001, doi:10.1088/1478-3975/12/5/056001.
  89. Hawkins-Daarud A, Rockne R, Corwin D, Anderson AR, Kinahan P, Swanson KR. (2015) In Silico Analysis Suggests Differential Response to Bevacizumab and Radiation Combination Therapy in Newly Diagnosed Glioblastoma. Roy. Soc. Interface, Aug 6;12(109). pii: 20150388, doi: 10.1098/rsif.2015.0388.
  90. Robertson-Tessia M , Gillies RJ, Gatenby RA, Anderson AR. (2015) Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes. Cancer Res. Apr 15;75(8):1567-79. doi: 10.1158/0008-5472.CAN-14-1428.
  91. Robertson-Tessia M and Anderson AR. (2015) Big Bang and context-driven collapse, Nature Genetics 47, 196–197,doi:10.1038/ng.3231.
  92. Scott JG, Fletcher AG, Maini PK, Anderson AR, Gerlee P. (2014) A filter-flow perspective of hematogenous metastasis offers a non-genetic paradigm for personalized cancer therapy, European Journal Of Cancer, doi: 10.1016/j.ejca.2014.08.019.
  93. Gerlee P, Kim E, Anderson ARA. (2014) Bridging scales in cancer progression: Mapping genotype to phenotype using neural networks. Semin Cancer Biol. Accepted. doi: 10.1016/j.semcancer.2014.04.013.
  94. Rebecca VW, Massaro R, Fedorenko IV, Gibney GT, Sondak VK, Anderson AR, Kim E, Amavaradi RK, Jin S, Maria-Engler SS, Messina JL, Gibney GT, Kudchadkar RR, Smalley KS (2014) Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma. Pigment Cell and Melanoma Research. Published online ahead of print February 3, 2014. DOI 10.1111/pcmr.12227.
  95. Scott JG, Hjelmeland AB, Chinnaiyan P, Anderson ARA, Basanta D (2014) Microenvironmental Variables Must Influence Intrinsic Phenotypic Parameters of Cancer Stem Cells to Affect Tumourigenicity. PLoS Comput Biol 10(1): e1003433. doi:10.1371/journal.pcbi.1003433.
  96. Gallaher J, Babu A, Plevritis S and Anderson ARA. (2014) Bridging population and tissue scale tumor dynamics: A new paradigm for understanding differences in tumor growth and metastatic disease. Cancer Res., Published OnlineFirst January 9, 2014. doi: 10.1158/0008-5472.CAN-13-0759.
  97. Kim E, Rebecca VW, Fedorenko, Messina JL, Mathew R, Maria-Engler SS, Basanta D, Smalley KS, Anderson ARA. (2013) Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach. Cancer Res. Published OnlineFirst September 30, 2013. doi:10.1158/0008-5472.CAN-13-1720.
  98. Basanta D, Anderson ARA. (2013) Exploiting ecological principles to better understand cancer progression and treatment. Interface Focus 3, 20130020, doi:10.1098/rsfs.2013.0020.
  99. Gallaher J, Anderson ARA. (2013) Evolution of intratumoral phenotypic heterogeneity: the role of trait inheritance. Interface Focus 3, 20130016, doi:10.1098/rsfs.2013.0016.
  100. Anderson ARA, Tomlin CJ, Couch J, and Gallahan D. (2013) Mathematics of the Integrative Cancer Biology Program. Interface Focus 3, 20130023, doi:10.1098/rsfs.2013.0023.
  101. Hawkins-Daarud A, Russell RC, Anderson AR and Swanson KR. (2013) Modeling tumor-associated edema in gliomas during anti-angiogenic therapy and its impact on imageable tumor. Front. Oncol. 3:66. doi: 10.3389/fonc.2013.00066.
  102. Scott JG, Basanta D, Anderson AR, Gerlee P. (2013) A mathematical model of tumor self-seeding reveals secondary metastatic deposits as drivers of primary tumor growth. J. R. Soc. Interface, 10(82), doi: 10.1098/rsif.2013.001.
  103. Scott JG, Kuhn P, Anderson AR. (2012) Unifying metastasis — integrating intravasation, circulation and end-organ colonization. Nat Rev Cancer. Published online 24 May 2012. doi:10.1038/nrc3287.
  104. Basanta D, Gatenby RA, Anderson AR. (2012) Exploiting evolution to treat drug resistance: Combination therapy and the double bind. Mol Pharm. [Epub ahead of print] PubMed PMID: 22369188.
  105. Rejniak K.A. and Anderson A.R.A. (2011) State of the art in computational modelling of cancer. Math Med Biol. [Epub ahead of print] PubMed PMID: 22200587.
  106. Basanta D, Scott JG, Fishman MN, Ayala G, Hayward SW, Anderson AR. (2011) Investigating prostate cancer tumour-stroma interactions - clinical and biological insights from an evolutionary game. Br J Cancer. doi: 10.1038/bjc.2011.517. [Epub ahead of print] PubMed PMID: 22134510.
  107. Flach EH, Rebecca VW, Herlyn M, Smalley KS, Anderson AR. (2011) Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance. Mol Pharm. [Epub ahead of print] PubMed PMID: 22067046.
  108. Swanson KR, Rockne RC, Claridge J, Chaplain MA, Alvord EC, Anderson AR. (2011) Quantifying the role of angiogenesis in malignant progression of gliomas: In silico modeling integrates imaging and histology. Cancer Res. [Epub ahead of print] PubMed PMID: 2190039.
  109. Scott JG, Basanta D, Chinnaiyan P, Canoll P, Swanson KR, Anderson AR. (2011) Production of 2-hydroxyglutarate by isocitrate dehydrogenase 1-mutated gliomas: an evolutionary alternative to the Warburg shift? Neuro Oncol. [Epub ahead of print] PubMed PMID: 21784755.
  110. Gu S, Chakraborty G, Champley K, Alessio AM, Claridge J, Rockne R, Muzi M, Krohn KA, Spence AM, Alvord EC Jr, Anderson AR, Kinahan PE, Swanson KR. (2011) Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images. Math Med Biol. [Epub ahead of print] PubMed PMID: 21562060.
  111. Gerlee P, Basanta D, Anderson AR. (2011) Evolving homeostatic tissue using genetic algorithms. Prog Biophys Mol Biol. 2011 Mar 22. [Epub ahead of print] PubMed PMID: 21419156.
  112. Kam Y, Rejniak KA, Anderson AR. (2011) Cellular modeling of cancer invasion: Integration of in silico and in vitro approaches. J Cell Physiol. 2011 Apr 4. doi: 10.1002/jcp.22766. [Epub ahead of print] PubMed PMID: 21465465.
  113. Silva A., Anderson A. R. A. and Gatenby R. (2011) A multiscale model of the bone marrow and hematopoiesis. Math Biosci Eng. 8 (2): 645-660.
  114. Paraiso KH, Xiang Y, Rebecca VW, Abel EV, Chen A, Munko AC, Wood E, Fedorenko IV, Sondak VK, Anderson AR, Ribas A, Dalla Palma M, Nathanson KL, Koomen JM, Messina JL, Smalley KS. (2011) PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression. Cancer Res. 2011 Feb 11. [Epub ahead of print] PubMed PMID: 21317224.
  115. Basanta D, Scott JG, Rockne R, Swanson KR, Anderson AR. (2011) The role of IDH1 mutated tumour cells in secondary glioblastomas: an evolutionary game theoretical view. Phys Biol. 8:015016. PubMed PMID: 21301070.
  116. Rejniak K. A., Quaranta V., Anderson A.R.A. (2010) Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma. IMA Math. Med. Biol. PubMed PMID: 21106672. doi:10.1093/imammb/dqq021.
  117. Rejniak KA, Wang SE, Bryce NS, Chang H, Parvin B, et al. (2010) Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling. PLoS Comput Biol 6(8): e1000900. doi:10.1371.
  118. Rejniak K.A. and Anderson A.R.A. Multiscale hybrid models of tumor growth. Wiley Interdisciplinary Reviews: System Biology and Medicine. 2010. Available on: http://dx.doi.org/10.1002/wsbm.102.
  119. Gillies R.J., Anderson A.R.A., Gatenby R.A., Morse D.L. The biology underlying molecular imaging in oncology: from genome to anatome and back again. Clinical Radiology. 2010 65: 517-521. PubMed PMID: 20541651.
  120. McDougall S.R., Chaplain M.A.J., Stephanou A., Anderson A.R.A. Modelling the Impact of Pericyte Migration and Coverage of Vessels on the Efficacy of Vascular Disrupting Agents. Math. Model. Nat. Phenom. 2010 5: 163-202.
  121. Gerlee P. and Anderson, A. R. A. Diffusion Limited Tumour Growth: Simulations and Analysis. Math Biosci Eng, 2010 7(2): 387-402. PubMed PMID: 20462295.
  122. Anderson AR, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, Basanta D, Weidow B, Narasanna A, Arteaga CL, Reynolds AB, Quaranta V, Estrada L, Weaver AM. Microenvironmental independence associated with tumor progression. Cancer Res. 2009 Nov 15;69(22):8797-806. Epub 2009 Nov 3. PubMed PMID: 19887618.
  123. Enderling H, Anderson AR, Chaplain MA, Beheshti A, Hlatky L, Hahnfeldt P. Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics. Cancer Res. 2009 Nov 15;69(22):8814-21. Epub 2009 Nov 3. PubMed PMID: 19887613.
  124. Strand DW, Franco OE, Basanta D, Anderson AR, Hayward SW. Perspectives on Tissue Interactions in Development and Disease. Curr Mol Med. 2009 Sep 13. [Epub ahead of print] PubMed PMID: 20205682.
  125. Basanta D, Strand DW, Lukner RB, Franco OE, Cliffel DE, Ayala GE, Hayward SW, Anderson AR. The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach. Cancer Res. 2009 Sep 1;69(17):7111-20. Epub 2009 Aug 25. PubMed PMID: 19706777.
  126. Kam Y, Karperien A, Weidow B, Estrada L, Anderson AR, Quaranta V. Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements. BMC Res Notes. 2009 Jul 13;2:130. PubMed PMID: 19594934.
  127. Hinow P, Gerlee P, McCawley LJ, Quaranta V, Ciobanu M, Wang S, Graham JM, Ayati BP, Claridge J, Swanson KR, Loveless M, Anderson AR. A spatial model of tumor-host interaction: application of chemotherapy. Math Biosci Eng. 2009 Jul;6(3):521-46. PubMed PMID: 19566124.
  128. Gerlee P, Lundh T, Zhang B, Anderson AR. Gene divergence and pathway duplication in the metabolic network of yeast and digital organisms. J R Soc Interface. 2009 Dec 6;6(41):1233-45. Epub 2009 Mar 18. PubMed PMID: 19324678.
  129. Ramis-Conde I, Chaplain MA, Anderson AR, Drasdo D. Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis. Phys Biol. 2009 Mar 25;6(1):16008. PubMed PMID: 19321920.
  130. Gerlee P, Anderson AR. Evolution of cell motility in an individual-based model of tumour growth. J Theor Biol. 2009 Jul 7;259(1):67-83. Epub 2009 Mar 12. PubMed PMID: 19285513.
  131. Popawski NJ, Agero U, Gens JS, Swat M, Glazier JA, Anderson AR. Front instabilities and invasiveness of simulated avascular tumors. Bull Math Biol. 2009 Jul;71(5):1189-227. Epub 2009 Feb 21. PubMed PMID: 19234746.
  132. Gerlee P, Anderson AR. Modelling evolutionary cell behaviour using neural networks: application to tumour growth. Biosystems. 2009 Feb;95(2):166-74. Epub 2008 Nov 5. PubMed PMID: 19026711.
  133. Anderson AR, Rejniak KA, Gerlee P, Quaranta V. Microenvironment driven invasion: a multiscale multimodel investigation. J Math Biol. 2009 Apr;58(4-5):579-624. Epub 2008 Oct 7. PubMed PMID: 18839176.
  134. Macklin P, McDougall S, Anderson AR, Chaplain MA, Cristini V, Lowengrub J. Multiscale modelling and nonlinear simulation of vascular tumour growth. J Math Biol. 2009 Apr;58(4-5):765-98. Epub 2008 Sep 10. PubMed PMID: 18781303.
  135. Quaranta V, Rejniak KA, Gerlee P, Anderson AR. Invasion emerges from cancer cell adaptation to competitive microenvironments: quantitative predictions from multiscale mathematical models. Semin Cancer Biol. 2008 Oct;18(5):338-48. Epub 2008 Apr 1. Review. PubMed PMID: 18524624.
  136. Enderling H, Alexander NR, Clark ES, Branch KM, Estrada L, Crooke C, Jourquin J, Lobdell N, Zaman MH, Guelcher SA, Anderson AR, Weaver AM. Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence. Biophys J. 2008 Sep;95(5):2203-18. Epub 2008 May 30. PubMed PMID: 18515372.
  137. Rejniak KA, Anderson AR. A computational study of the development of epithelial acini: II. Necessary conditions for structure and lumen stability. Bull Math Biol. 2008 Jul;70(5):1450-79. Epub 2008 Apr 10. PubMed PMID: 18401665.
  138. Ramis-Conde I, Drasdo D, Anderson AR, Chaplain MA. Modeling the influence of the E-cadherin-beta-catenin pathway in cancer cell invasion: a multiscale approach. Biophys J. 2008 Jul;95(1):155-65. Epub 2008 Mar 13. PubMed PMID: 18339758.
  139. Anderson AR, Quaranta V. Integrative mathematical oncology. Nat Rev Cancer. 2008 Mar;8(3):227-34. PubMed PMID: 18273038.
  140. Enderling H, Chaplain MA, Anderson AR. A model of breast carcinogenesis and recurrence after radiotherapy. PAMM (ICIAM07 Proceedings), 2008; doi:10.1002/pamm.200700362.
  141. Ramis-Conde I, Chaplain MA, Anderson AR. Mathematical modelling of cancer cell invasion of tissue. Math. Comput. Modell. 2008; 47, 533-545.
  142. Georgescu W, Jourquin J, Estrada L, Anderson AR, Quaranta V, Wikswo JP. Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices. Lab Chip. 2008 Feb;8(2):238-44. Epub 2007 Dec 21. PubMed PMID: 18231661.
  143. Anderson AR, Rejniak KA, Gerlee P, Quaranta V. Modelling of cancer growth, evolution and invasion: Bridging Scales and Models. Math. Mod. Nat. Phenom., 2007; 2: 1-29.
  144. Rejniak KA, Anderson AR. A computational study of the development of epithelial acini: I. Sufficient conditions for the formation of a hollow
    structure. Bull Math Biol. 2008 Apr;70(3):677-712. Epub 2008 Jan 11. PubMed PMID: 18188652.
  145. Gerlee P, Anderson AR. A hybrid cellular automaton model of clonal evolution in cancer: the emergence of the glycolytic phenotype. J Theor Biol. 2008 Feb 21;250(4):705-22. Epub 2007 Nov 4. PubMed PMID: 18068192.
  146. Gerlee P, Anderson AR. Stability analysis of a hybrid cellular automaton model of cell colony growth. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 May;75(5 Pt 1):051911. Epub 2007 May 17. PubMed PMID: 17677102.
  147. Pearce IG, Chaplain MA, Schofield PG, Anderson AR, Hubbard SF. Chemotaxis-induced spatio-temporal heterogeneity in multi-species host-parasitoid systems. J Math Biol. 2007 Sep;55(3):365-88. Epub 2007 Apr 14. PubMed PMID: 17435998.
  148. Gerlee P, Anderson AR. An evolutionary hybrid cellular automaton model of solid tumour growth. J Theor Biol. 2007 Jun 21;246(4):583-603. Epub 2007 Feb 12. PubMed PMID: 17374383.
  149. Enderling H, Chaplain MA, Anderson AR, Vaidya JS. A mathematical model of breast cancer development, local treatment and recurrence. J Theor Biol. 2007 May 21;246(2):245-59. Epub 2006 Dec 12. PubMed PMID: 17289081.
  150. Anderson AR, Weaver AM, Cummings PT, Quaranta V. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell. 2006 Dec 1;127(5):905-15. PubMed PMID: 17129778.
  151. Chaplain MA, McDougall SR, Anderson AR. Mathematical modeling of tumor-induced angiogenesis. Annu Rev Biomed Eng. 2006;8:233-57. Review. PubMed PMID: 16834556.
  152. Pearce IG, Chaplain MA, Schofield PG, Anderson AR, Hubbard SF. Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications. J Theor Biol. 2006 Aug 21;241(4):876-86. Epub 2006 Mar 20. PubMed PMID: 16546216.
  153. Schor SL, Ellis IR, Harada K, Motegi K, Anderson AR, Chaplain MA, Keatch RP, Schor AM. A novel 'sandwich' assay for quantifying chemo-regulated cell migration within 3-dimensional matrices: wound healing cytokines exhibit distinct motogenic activities compared to the transmembrane assay. Cell Motil Cytoskeleton. 2006 May;63(5):287-300. PubMed PMID: 16528704.
  154. Enderling H, Anderson AR, Chaplain MA, Rowe, GW. Visualisation of the Numerical Solution of Partial Differential Equation Systems in Three Space Dimensions and its Importance for Mathematical Models in Biology. Math. Biosci. Eng. 2006; 3: 571-582.
  155. McDougall SR, Anderson AR, Chaplain MA. Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications and therapeutic targeting strategies. J Theor Biol. 2006 Aug 7;241(3):564-89. Epub 2006 Feb 17. PubMed PMID: 16487543.
  156. Enderling H, Anderson AR, Chaplain MA, Munro AJ, Vaidya JS. Mathematical modelling of radiotherapy strategies for early breast cancer. J Theor Biol. 2006 Jul 7;241(1):158-71. Epub 2005 Dec 28. PubMed PMID: 16386275.
  157. McDougall SR, Anderson AR, Chaplain MA, Sherratt JA. Mathematical modelling of flow in 2D and 3D vascular networks: Applications to anti-angiogenic and chemotherapeutic drug strategies, (2005). Math. Comput. Modell., 41: 1137-1156.
  158. Quaranta V, Weaver AM, Cummings PT, Anderson AR. Mathematical modeling of cancer: the future of prognosis and treatment. Clin Chim Acta. 2005 Jul 24;357(2):173-9. Review. PubMed PMID: 15907826.
  159. Ayati BP, Webb GF, Anderson, AR. Computational methods and results for structured multiscale models of tumor invasion. Multiscale Mod. Sim. 2005; 5: 1-20.
  160. Anderson AR, Vasiev BN. An individual based model of rippling movement in a myxobacteria population. J Theor Biol. 2005 Jun 7;234(3):341-9. Epub 2005 Jan 20. PubMed PMID: 15784269.
  161. Anderson AR. A hybrid mathematical model of solid tumour invasion: the importance of cell adhesion. Math Med Biol. 2005 Jun;22(2):163-86. Epub 2005 Mar 21. PubMed PMID: 15781426.
  162. Stephanou A, McDougall SR, Anderson AR, Chaplain MA. Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies. Bull Math Biol. 2002 Jul;64(4):673-702. PubMed PMID: 12216417.
  163. Farnsworth KD, Anderson AR. How Simple Grazing Rules Lead Can Lead to Persistent Boundaries in Vegetation Communities (2001). Oikos, 95: 15-24.
  164. Pitcairn AW, Chaplain MA, Weijer CJ, Anderson A R. A Discrete-Continuum Mathematical Model of Dictyostelium Aggregation (2000). ECMTB., 2: 6-11.
  165. Anderson AR, Chaplain MA, Garcia-Reimbert C, Vargas CA. A Gradient-Driven Mathematical Model of Anti-Angiogenesis (2000). Math. Comp. Model., 32: 1141-1152.
  166. Anderson AR, Chaplain MA, Newman EL, Steele RJ, Thompson AM. Mathematical Modelling of Tumour Invasion and Metastasis (2000). J. Theoret. Med., 2: 129-154.
  167. Davidson FA, Anderson AR, Chaplain MA. Steady State Solutions of a Generic Model for the Formation of Capillary Networks (2000). App. Math. Letters, 13: 127-132.
  168. Baum M, Chaplain MA, Anderson AR, Douek M, Vaidya JS. Does breast cancer exist in a state of chaos? Eur J Cancer. 1999 Jun;35(6):886-91. Review. PubMed PMID: 10533467.
  169. Sleeman BD, Anderson AR, Chaplain MA. A Mathematical Analysis of a Model for Capillary Network Formation in the Absence of Endothelial Cell Proliferation.1999; Appl. Math. Lett. 12: 121-127.
  170. Anderson AR, Chaplain MA. Continuous and discrete mathematical models of tumor-induced angiogenesis. Bull Math Biol. 1998 Sep;60(5):857-99. PubMed PMID: 9739618.
  171. Chaplain MA, Anderson AR. Mathematical modelling, simulation and prediction of tumour-induced angiogenesis. Invasion Metastasis. 1996;16(4-5):222-34. Review. PubMed PMID: 9311387.
  172. Anderson AR, Chaplain MA. A Mathematical Model for Capillary Network Formation in the Absence of Endothelial Cell Proliferation. (1997). App. Math. Letters, 11: 109-114.
  173. Anderson AR, Young IM, Sleeman BD, Griffiths BS. Nematode movement along a chemical gradient in a structurally heterogeneous environment: I. Experiment. (1997). Fundam. appl. Nematol., 20: 157-164.
  174. Anderson AR, Sleeman BD, Young IM, Griffiths BS. Nematode movement along a chemical gradient in a structurally heterogeneous environment: II. Theory. (1997). Fundam. appl. Nematol., 20: 165-172.
  175. Anderson AR, Sleeman BD. Wave front propagation and its failure in coupled systems of discrete bistable cells modelled by FitzHugh-Nagumo dynamics. (1995). Int. J. Bif. Chaos, 5: 63-74.

Contributed Book Chapters

  1. Scott JG, Gerlee P, Basanta D, Fletcher AG, Maini PK, Anderson AR. Mathematical Modeling of the Metastatic Process, in Experimental Metastasis: Modeling and Analysis, ed. A. Malek (2013) Springer: New York, Chapter 9, 189-208.
  2. Anderson AR, McDougall S, Chaplain MA. A Hybrid Discrete-Continuum Model of Tumor-Induced Angiogenesis, in Modeling Tumor Vasculature: Molecular, Cellular and Tissue Level Aspects and Implications, ed. T.L. Jackson (2012) Springer: New York, Chapter 5, 105-134.
  3. Chaplain MA, McDougall S, Anderson AR. Blood Flow and Tumour-Induced Angiogenesis: Dynamically Adapting Vascular Networks, in Modeling Tumor Vasculature: Molecular, Cellular and Tissue Level Aspects and Implications, ed. T.L. Jackson (2012) Springer: New York, Chapter 8, 167-212.
  4. Anderson AR, Basanta D, Gerlee P, Rejniak KA. Evolution, Regulation and Disruption of Homeostasis and its Role in Carcinogenesis, in Multiscale Cancer Modeling, eds. Thomas S. Deisboeck and Georgios Stamatakos (2010) CRC Press: London, 1-30.
  5. Chaplain MA, Macklin P, McDougall S, Anderson AR, Cristini V, Lowengrub J. Multiscale Mathematical Modeling of Vascular Tumor Growth: An Exercise in Transatlantic Cooperation, in Multiscale Cancer Modeling, eds. Thomas S. Deisboeck and Georgios Stamatakos (2010) CRC Press: London, 251-306.
  6. Anderson AR. M for Invasion: Morphology, Mutation and the Microenvironment, in Selected Topics on Cancer Modelling Genesis - Evolution - Immune Competition - Therapy, eds. N. Bellomo, M. Chaplain, and E. De Angelis (2008) Birkhauser, Boston, 277-298.
  7. Anderson AR. Hybrid Multiscale Model of Tumour Invasion: Evolution and the Microenvironment, in Single-Cell-Based Models in Biology and Medicine, eds. A. R. A. Anderson, M. A. J. Chaplain, K. A. Rejniak (2007) Birkhauser: Basel, 3-28.
  8. Chaplain MA, Anderson AR. Mathematical Modelling of Tumour-induced Angiogenesis: Network Growth and Structure, in Angiogenesis in Brain Tumours, eds. M. Kirsch, P. McL. Black (2004) Kluwer, 51-75.
  9. Anderson AR. Solid Tumour Invasion: The Importance of Cell Adesion, in Function and Regulation of Cellular Systems: Experiments and Models, eds. A. Deutsch, M. Falcke, J. Howard, W. Zimmermann (2003) Birkhäuser,379-389.
  10. Anderson AR, Pitairn A. Application of the Hybrid Discrete-Continuum Technique, in Polymer and Cell Dynamics, eds. W. Alt, M. Chaplain, M. Griebel, J. Lenz (2003) Birkhauser, 261-279.
  11. Anderson AR. A Hybrid Discrete-Continuum Technique for Individual Based Migration Models, in Polymer and Cell Dynamics, eds. W. Alt, M. Chaplain, M. Griebel, J. Lenz (2003) Birkhauser, 251-259.
  12. Anderson AR. The Effects of Cell Adhesion on Solid Tumour Geometry, in Morphogenesis and Pattern Formation in Biological Systems, eds. T. Sekimura, S. Noji, N. Ueno, P. Maini (2003) Springer, 315-325.
  13. Chaplain MA, Anderson AR. Mathematical Modelling of Tissue Invasion, in Cancer Modelling and Simulation, ed. L. Preziosi (2003) Chapman and Hall, 269-297.
  14. Chaplain MA, Anderson AR. Modelling the Growth and Form of Capillary Networks, chapter 13, pp225-250, in On Growth and Form: Spatio-temporal Pattern Formation in Biology, eds. M.A.J. Chaplain, G.D. Singh, J. McLachlan (1999) Wiley: Chichester, 225-249.

Edited Books

  1. Single-Cell-Based Models in Biology and Medicine, eds. A. R. A. Anderson, M. A. J. Chaplain, K. A. Rejniak (2007) Birkhauser: Basel

Popular Press

  1. Cancer is complex and dynamic - ergo, dose optimization calls for mathematical modeling by Alexander R. A. Anderson, Robert Gillies, Robert Gatenby, The Cancer Letter, Vol 48, Issue 19, May 13th, 2022.
  2. A New Approach to Cancer Treatment Draws Lessons From Darwin by Brianna Abbott, Wall Street Journal, January 7th, 2020.
  3. Adapting for survival by Ann Miller Baker, Momentum, Vol 4, Issue 2, 2018.
  4. Virtual trials in virtual patients by Marc Beishon, Cancer World, August 2nd, 2017.
  5. The cancer equation: Mathematically modelling the cure by Alexander Nazaryan, The Indendent, April 9th, 2014.
  6. At Moffitt, math modeling aims to generate new treatments for cancer by Robert Trigaux, Tampa Bay Times, April 8th, 2014.
  7. Getting Cancer Wrong by Alexander Nazaryan, Newsweek, Cover story, March issue, 2014.
  8. Opinion: Calculating Cancer by Alexander Anderson and Robert Gatenby, The Scientist, January 6, 2014.
  9. Pushing Boundaries, Inciting Innovation by Sarah E. Hoffe, MD, Florida MD, Cover story, October Issue, 2013.
  10. Medical Math: Mathematicians doing cancer research by Amy Keller, Florida Trend, May Issue, 2013.