To modulate or to skip: De-escalating PARP inhibitor maintenance therapy.
History of treatment scheduling as impacted by mathematical modelling.
Metastases represented by a planetary system with the sun as a primary tumor, by Jill Gallaher.
Trends in Cell Biology Cover 2023
Showing a set of simulated tumors, color-coded according to immune interactions, by Jeff West.
Showing multiple phase planes geometrically arranged, by Maxi Srobl.
Colored discs indicate repeatable treatment cycles, Jeff West.
Finding the goldilocks window of Chemotherapy, by Derek Park.
Evolution of metabolically heterogeneous tumors, by Mark Robertson-Tessi.
In vitro & in silico metabolic phenotypes, by Mark Robertson-Tessi & Mehdi Damaghi.
Sliced in half, revealing inner core.
3D Reconstruction of In Silico Tumor
Distribution of colors highlights the individual cells that makeup the tumor.
Passing through an In Silico Tumor
Visualization of the 2D slices through a 3D tumor, highlighting the fingering morphology.
Two orthogonal slices of a 3D Tumor
Each slice is 10 cells thick and highlights the fingering morphology that emerges.
Highlighting the millions of individual cells that makeup the tumor.
Highlighting the influence a homogeneous ECM has on an invading tumor.
Highlighting the influence a random ECM has on an invading tumor.
A neural network representation of a computation cells internal signaling.
Panel of simulations investigating the role of the microenvironment in driving glycolysis.
Oxygen deprived microenvironment drives the glycolytic phenotype.
Evolutionary sequence of dominant phenotypes growing in a tumor.
Growth and invasion of a potts model generated tumor.
Simulation of a prostate cancer that rapidly dies out.
Purely continuous representation of and invading tumor in a heterogeneous ECM.
3 Dimnesional In Silico Angiogensis
Angiogenic response to a tumor located at the base of the cube (not shown).