Published: Antifragility in Complex Systems

Jeffrey West
Written by Jeffrey West on
Published: Antifragility in Complex Systems

Some good news from EDIT Lab: we have just published a Perspective piece in npjComplexity called “Antifragility in Complex Systems.” The paper is joint work with the Applied Antifragility Working Group (AAWG; https://www.antifragility.science/). The AAWG is composed of a talented group of scientists with backgrounds in both natural/biological sciences and physical/technical disciplines. Therefore, the paper reviews applications of antifragility both in man-made, physical systems as well as natural biological systems. Drawing from complexity science, we review the role of nonlinearity in input/output relationships within complex systems and note for the first time different scales of antifragility: intrinsic (input–output nonlinearity), inherited (extrinsic environmental signals), and induced (feedback control), with associated counterparts in biological systems: ecological (homogeneous systems), evolutionary (heterogeneous systems), and interventional (control).

Jeffrey West

Jeffrey West

Studying the dynamics of cell-cell interactions that influence tumor evolution, heterogeneity, and treatment resistance.

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