Publications
List of publications ranked by year:
- Authors Title Pubmed ID: number
2008 to 2010
- Berndt N, Yang H, Trinczek B, Betzi S, Zhang Z, Wu B, Lawrence NJ, Pellecchia M, Schönbrunn E, Cheng JQ, Sebti SM. The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane. Cell Death Differ. 2010 May 21. Pubmed ID: 20489726
- Han H, Yang Y, Olesen SH, Becker A, Betzi S, Schönbrunn E. The Fungal Product Terreic Acid is a Covalent Inhibitor of the Bacterial Cell Wall Biosynthetic Enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) (2010). Biochemistry. 49:4276-82 Pubmed ID: 20392080
- Mahajan K, Coppola D, Challa S, Fang B, Chen YA, Zhu W, Lopez AS, Koomen J, Engelman RW, Rivera C, Muraoka-Cook RS, Cheng JQ, Schönbrunn E, Sebti SM, Earp HS, Mahajan NP (2010). Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation. PLoS One 5:e9646. Pubmed ID: 20333297
- Phan J, Li Z, Kasprzak A, Li B, Sebti S, Guida W, Schönbrunn E, Chen J. Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX. J Biol Chem. 2010 Jan 15;285(3):2174-83. Pubmed ID: 19910468
- Funke T, Yang Y, Han H, Healy-Fried M, Olesen S, Becker A, Schönbrunn E. Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli. J Biol Chem. 2009 Apr 10;284(15):9854-60. Pubmed ID: 19211556
- Alontaga AY, Rodriguez JC, Schönbrunn E, Becker A, Funke T, Yukl ET, Hayashi T, Stobaugh J, Moënne-Loccoz P, Rivera M. Structural characterization of the hemophore HasAp from Pseudomonas aeruginosa: NMR spectroscopy reveals protein-protein interactions between Holo-HasAp and hemoglobin. Biochemistry. 2009 Jan 13;48(1):96-109. Pubmed ID: 19072037
- Wang A, Rodríguez JC, Han H, Schönbrunn E, Rivera M. X-ray crystallographic and solution state nuclear magnetic resonance spectroscopic investigations of NADP+ binding to ferredoxin NADP reductase from Pseudomonas aeruginosa. Biochemistry. 2008 Aug 5;47(31):8080-93. Pubmed ID: 18605699
2003 to 2008
- Funke T, Healy-Fried M, Han H, Alberg D, Bartlett P, Schonbrunn E. Differential Inhibition of Class I and Class II5-Enolpyruvylshikimate-3-phosphate Synthases by Tetrahedral Reaction Intermediate Analogues. Biochemistry. 2007 Nov 20;46(46):13344-13351. Pubmed ID: 17958399
- Healy-Fried M, Funke T, Priestman M, Han H, Schonbrunn E. Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase. J Biol Chem. 2007 Nov 9;282(45):32949-32955. Pubmed ID: 17855366
- Wang A, Zeng Y, Han H, Weeratunga S, Morgan B, Moenne-Loccoz P, Schonbrunn E, Rivera M. Biochemical and structural characterization of Pseudomonas aeruginosa Bfd and FPR: ferredoxin NADP+ reductase and not ferredoxin is the redox partner of heme oxygenase under iron-starvation conditions. Biochemistry. 2007 Oct 30;46(43):12198-12211. Pubmed ID: 17915950
- Funke T, Han H, Healy-Fried M, Fischer M, Schonbrunn E. Molecular basis for the herbicide resistance of Roundup Ready crops. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13010-13015. Pubmed ID: 16916934
- Li Q, Hanzlik R, Weaver R, Schonbrunn E. Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core. Biochemistry. 2006 Jan 24;45(3):701-708. Pubmed ID: 16411745
- Eschenburg S, Priestman M, Abdul-Latif F, Delachaume C, Fassy F, SchonbrunnE. A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA). J Biol Chem. 2005 Apr 8;280(14):14070-14075. Pubmed ID: 15701635
- Eschenburg S, Priestman M, Schonbrunn E. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release. J Biol Chem. 2005 Feb 4;280(5):3757-3763. Pubmed ID: 15531591
- Priestman M, Funke T, Singh I, Crupper S, Schonbrunn E. 5-Enolpyruvylshikimate-3-phosphate synthase from Staphylococcus aureus isinsensitive to glyphosate. FEBS Lett. 2005 Jan 31;579(3):728-732. Pubmed ID: 15670836
- Priestman M, Healy M, Becker A, Alberg D, Bartlett P, Lushington G, Schonbrunn E. Interaction of phosphonate analogues of the tetrahedral reaction intermediate with 5-enolpyruvylshikimate-3-phosphate synthase in atomic detail. Biochemistry. 2005 Mar 8;44(9):3241-3248. Pubmed ID: 15736934
- Priestman M, Healy M, Funke T, Becker A, Schonbrunn E. Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate. FEBS Lett. 2005 Oct 24;579(25):5773-5780. Pubmed ID: 16225867
- Eschenburg S, Kabsch W, Healy M, Schonbrunn E. A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate states. J Biol Chem. 2003 Dec 5;278(49):49215-49222. Pubmed ID: 13129913
Before 2003
- Eschenburg S, Healy M, Priestman M, Lushington G, Schonbrunn E. How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl shikimate-3-phosphate synthase from Escherichia coli. Planta. 2002 Nov;216(1):129-135.. Pubmed ID: 12430021
- Eschenburg S, Schonbrunn E. Comparative X-ray analysis of the un-liganded fosfomycin-target murA. Proteins. 2000 Aug 1;40(2):290-298. Pubmed ID: 10842342
- Schonbrunn E, Eschenburg S, Krekel F, Luger K, Amrhein N. Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA. Biochemistry. 2000 Mar 7;39(9):2164-2173. Pubmed ID: 10694381
- Schonbrunn E, Eschenburg S, Luger K, Kabsch W, Amrhein N. Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6345-6349. Pubmed ID: 10823915
- Schonbrunn E, Phlippen W, Trinczek B, Sack S, Eschenburg S, Mandelkow E, Mandelkow E. Crystallization of a macromolecular ring assembly of tubulin liganded with the anti-mitotic drug podophyllotoxin. J Struct Biol. 1999 Dec 15;128(2):211-215. Pubmed ID: 10600574
- Macheroux P, Schonbrunn E, Svergun D, Volkov V, Koch M, Bornemann S, Thorneley R. Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding. Biochem J. 1998 Oct 15;335 ( Pt 2):319-327. Pubmed ID: 9761730
- Schonbrunn E, Svergun D, Amrhein N, Koch M. Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA). Eur J Biochem. 1998 Apr 15;253(2):406-412. Pubmed ID: 9654090
- Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow E, Mandelkow E. The crystal structure of dimeric kinesin and implications for microtubule-dependent motility. Cell. 1997 Dec 26;91(7):985-994. Pubmed ID: 9428521
- Kozielski F, Schonbrunn E, Sack S, Muller J, Brady S, Mandelkow E. Crystallization and preliminary X-ray analysis of the single-headed and double-headed motor protein kinesin. J Struct Biol. 1997 Jun;119(1):28-34. Pubmed ID: 9216086
- Sack S, Dauter Z, Wanke C, Amrhein N, Mandelkow E, Schonbrunn E. Crystallization and preliminary X-ray diffraction analysis of UDP-N-acetylglucosamine enolpyruvyltransferase of Enterobacter cloacae. J Struct Biol. 1996 Jul;117(1):73-76. Pubmed ID: 8776890
- Schonbrunn E, Sack S, Eschenburg S, Perrakis A, Krekel F, Amrhein N, Mandelkow E. Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin. Structure. 1996 Sep 15;4(9):1065-1075. Pubmed ID: 8805592
- Schweers O, Schonbrunn-Hanebeck E, Marx A, Mandelkow E. Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure. J Biol Chem. 1994 Sep 30;269(39):24290-24297. Pubmed ID: 7929085
- Schonbrunn-Hanebeck E, Laber B, Amrhein N. Slow-binding inhibition of the Escherichia coli pyruvate dehydrogenase multienzyme complex by acetylphosphinate. Biochemistry. 1990 May 22;29(20):4880-4885. Pubmed ID: 2194562
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