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Anti Cancer Targets

MDMX: 3JZO, 3JZP, 3JZQ

MDM2: 3JZR, 3JZS

MDMX function as key regulators of p53 by binding to its N terminus, inhibiting its transcriptional activity, and promoting degradation.

Anti Bacterial Target

EPSPS (3-phosphoshikimate 1-carboxyvinyltransferase): 3FJX, 3FJZ, 3FK0, 3FK1, 2PQ9, 2PQB, 2PQC, 2PQD, 2QFQ, 2QFS, 2QFT, 2QFU, 2GG4, 2GG6, 2GGA, 2GGD, 2AA9, 1X8R, 1X8T, 1Q36, 1MI4, 1G6S, 1G6T

Anti Bacterial Target

MurA (UDP-N-acetylglucosamine 1-carboxyvinyltransferase): 1YBG, 1RYW, 1Q3G, 1EJC, 1EJD, 1EYN, 1DLG

HasAp (Hemophore from Pseudomonas aeruginosa): 3ELL

Ferredoxin-NADP Reductase: 3CRZ, 2QDX

Human Calpain: 1ZCM

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