Our research focuses on mathematical modeling and computational simulations of tumor initiation, progression and treatment. Computational simulations give the unique opportunity for testing various scenarios of tumor emergence and growth, as well as different protocols of chemo-, radio-, immuno-, hormone- and combined therapies. In particular, we are interested in investigating the bio-mechanics of normal vs. tumor-like tissue morphogenesis, micro-fluids in drug delivery and bio-physics of tumor microenvironment using the IBCell model (immersed boundary model of a cell), the micro/macroPD (regularized Stokeslets method of micro- and macro-pharmacodynamics), or the 3DMultiCell (multiscale mulicellular spheroids) models.
|We are/were funded by:|
|NIH/NCI Physical Science-Oncology Projects (Vanderbilt-Moffitt U01)|
|NIH/NCI Integrative Cancer Biology Program (Vanderbilt-Moffitt ICBP)|
|NIH/NCI Physical Science-Oncology Center Program (Moffitt PSOC)|
|Miles for Moffitt Milestones Research Award|
|American Cancer Society-Institutional Research Grant|